the klotho conference
Speakers
our speakers
meet the speakers
The Klotho Conference will feature an impressive lineup of thought leaders, researchers, drug developers, executives, clinicians, analysts and investors at the forefront of Klotho-related science and industry.
Dr. Hagai Ligumsky
Dr. Ligumsky, MD, PhD, is a medical oncology specialist at the Tel Aviv Sourasky Medical Center, where he specializes in gastrointestinal and genitourinary malignancies, as well as precision oncology. He also conducts translational research.
Lewis Rumpler
Lewis Rumpler is CEO of Alpha-Young, LLC, a California-based biotech company developing novel therapeutics for cardiorenal applications. Lewis is a serial entrepreneur and life sciences executive with over 40 years of experience in biotech/pharma.
Dr. Gwendalyn King
Dr. Gwendalyn King is Associate Professor at Creighton University. Her research is on changes that occur in the brain as a result of normal aging and understanding the breakpoints between normal aging and development of neurodegenerative diseases.
Dr. Manfred Stangl
Dr. Manfred Stangl, MD, is the CSO of Kyttaro Therapeutics. He is also the head of Renal and Pancreas Transplant Service, LMU Munich. Dr. Stangl has 25+ years of surgical experience and is the recipient of Heinz Maier Leibnitz-Medaille.
Nancy Kelley
Nancy Kelley is the CEO of Kyttaro Therapeutics. Previously she was Founding Executive Director of the New York Genome Center and led several additional biotech initiatives. She holds JD/MPP degrees from Harvard and a BA from Yale.
Agustin Fernandez Santana III
Founder and CEO of Klothea Bio, Rational Vaccines, Founder and Chairman of ADvantage Therapeutics. Mr. Fernandez is a 9-time EMMY award winning writer/director/producer and the executive producer of a 2014 academy award winning documentary.
Dr. Christopher Yanucil
Dr. Yanucil is CTO of Alpha-Young. Hs Ph.D. and post-doctoral work focused on the crosstalk between FGF23 and Klotho in the regulation of signal transduction and cardiac remodeling. He developed a protocol for purifying recombinant Klotho protein.
Dr. Albert Agro
Dr. Albert Agro, CEO of Jocasta Neuro, is a seasoned biotech executive with a strong background in human biology and medicine. During his career, he has founded three companies, led two successful IPOs and has overseen two acquisitions.
Dr. Joseph Sinkule
Dr. Sinkule is the CEO, Founder, and Chairman of the Board of Directors of Klotho Neurosciences. He has over 40 years of drug, biologic, and medical device development and commercialization experience.
Mac Davis
Mac is the Founder and CEO of Minicircle, driving the organization’s long-term vision, trajectory and strategy. A true pioneer in biotech, Mac is intent on pushing the boundaries of medicine and technology to challenge disease and death.
Dr. Steven S. Welc
Dr. Steven Welc, PhD, is an Assistant Professor at Indiana University School of Medicine. His research is focused on understanding the molecular mechanisms that regulate muscle function and pathophysiology.
Dr. Ira Frahmand
Dr. Ira Frahmand is a senior scientist at the University of Wisconsin Alzheimer’s Disease Research Center. Her research is geared toward a detailed understanding of the anatomical and functional organization of cognitive processes.
Dr. Jens Eckstein
Dr. Jens Eckstein is an accomplished life sciences investor and entrepreneur, currently serving as an Investment Partner at Hevolution. He has over two decades of experience in venture capital, company formation, and strategic advisory roles.
Fiona Miller
Fiona Miller is the founder and managing partner of quadrascope, a venture capital firm focused on disease prevention and biological age reversal. She is a serial entrepreneur with three successful exits.
Dr. Gail Humble
Dr. Gail Humble, CEO of Klotho Skin, has 25+ years researching the Klotho gene. She patented methods to upregulate Klotho in stem cells, authored clinical trials, and co-founded Klotho Longevity, competing in the XPRIZE. She is a noted global speaker
Dr. Christian Faul
Dr. Christian Faul is a UAB professor studying FGF and klotho signaling in kidney and heart disease. He founded Alpha Young LLC to develop klotho-based therapies and trains award-winning students in cardiovascular and renal research.
Howard Leonhardt, hPhD
Howard Leonhardt is an inventor with 42+ patents in cardiovascular and regenerative medicine. His innovations have treated 600,000+ patients and power startups in longevity, aesthetics, and age reversal across 124 global wellness clinics.
Dr. Leslie Miller
Dr. Leslie Miller, CMO at Leonhardt Ventures, is a global cardiology expert with 35+ years of experience, 250+ publications, and leadership in 90+ clinical trials. He’s a pioneer in heart failure, stem cell therapy, and cardiovascular regeneration.
Dr. Miguel Chillon
Dr. Miguel Chillon is an ICREA Research Professor at UAB and gene therapy expert. He develops viral vectors and chronokine-based treatments for neurodegeneration and aging, with 85+ publications, 14 patents, and two biotech spin-offs.
Dr. Makoto Kuro-o
Dr. Makoto Kuro-O is a physician-scientist known for discovering the klotho gene. His research focuses on how Klotho proteins and endocrine FGFs regulate aging, metabolism, and energy homeostasis to develop therapies for age-related diseases.
Dr. Carmela Abraham
Dr. Carmela Abraham, CSO of ADvantage Therapeutics and Klothea Bio, is a Harvard-trained neuroscientist advancing Klotho-based therapies for Alzheimer’s and MS. Her 30+ years of research have earned awards from NIH and the Alzheimer’s Association.
Menachem Abraham
Menachem Abraham is a tech & biotech entrepreneur. Currently Managing Partner of Mendu Capital LLC. He was CEO and co-founder of Klogenix, Mintera and Prominet as well as CTO of Chipcom, a NASDAQ listed company in 1991-1995 and served on Boards.
Join us on September 17-18, 2026
The second annual Klotho conference will bring together virtually leading scientists, drug developers, clinicians, thought leaders, analysts and investors to foster vibrant discussions and debate on the future of Klotho-based therapies and diagnostics.