Dr. Radosveta Koldamova is a Professor of Translational Neuroscience whose research focuses on the molecular mechanisms underlying Alzheimer’s disease, particularly involving APOE, TREM2, ABCA7, and related genes. Her lab uses Alzheimer’s model mice expressing human APOE isoforms to explore late-onset disease processes through behavioral testing, immunohistochemistry, transcriptomics, and lipidomics. Dr. Koldamova has extensive experience analyzing high-throughput sequencing data, including transcription factor binding and histone modifications, to assess the brain’s response to environmental toxicants, dietary patterns, and therapeutic agents. Her work aims to bridge mechanistic discovery and potential treatment strategies for neurodegenerative disease.